Ammasi Periasamy, Ph.D.

Professor, Center Director

Biology, University of Virginia
B005 Physical and Life Sciences Building (PLSB), White Head Rd.,
Charlottesville, VA 22904

Brief Biosketch

Prof. Ammasi Periasamy received his M.S. in Physics (Annamalai University, Tamil Nadu) and M.S./Ph.D. in Biomedical engineering (Imaging) from the Indian Institute of Technology, Madras, India. Postdoctoral training in Biomedical Imaging (light microscopy) was at the University of Washington, Seattle. Prof. Periasamy worked at the University of North Carolina at Chapel Hill and he developed fluorescence lifetime imaging microscopy (FLIM) for measuring the oscillations in cytosolic and nuclear free calcium in single intact living cells. Prof. Periasamy joined the University of Virginia and is currently working as a Professor of Biology and Biomedical Engineering.

Prof. Periasamy is an internationally recognized expert in advanced microscopy techniques, particularly in the area of molecular imaging in living cells, tissue and animal. A key area of his research is focused on the design and development of optical methodology including advanced light microscopy techniques to investigate/monitor exogenous and endogenous protein-protein interactions, intravital imaging and monitoring the physical parameters of normal versus cancer cells/tissues. Prof. Periasamy is the founder and center director of the internationally known W.M. Keck Center for Cellular Imaging (KCCI; http://www.kcci.virginia.edu/). Prof. Periasamy is one of the pioneers in the development of fluorescence lifetime imaging microscopy (FLIM) for measuring the oscillations in cytosolic and nuclear free calcium in single intact living cells. He developed a 2- and 3-color steady state, confocal, multiphoton, and FLIM based Förster resonance energy transfer (FRET) imaging system for protein localization in living specimens. He has published over 100 articles in refereed journals and book chapters. http://kcci.virginia.edu/peri-publications He has given more than 100 invited lectures nationally and internationally. Prof. Periasamy has edited three books, series book editor on cellular and clinical imaging (6 books), http://kcci.virginia.edu/publications/books Chairperson in organizing an annual International conference on Multiphoton Microscopy in the Biomedical Sciences through SPIE (since 2001) and runs a hands on training annual workshop  on FLIM & FRET Microscopy at the University of Virginia, Charlottesville during March (since 2002). http://kcci.virginia.edu/workshop Prof. Periasamy was elected “Fellow” members of the SPIE Optical Society in 2012.    

List of Publications